The Tucson Regional was widely considered the toughest of the 16 in the NCAA tournament. Host Arizona found out just how tough, becoming the first national seed eliminated.

Dallas Baptist knocked out the No. 13 Wildcats with a 7-0 win Saturday, less than 24 hours after Grand Canyon, the No. 4 regional seed, beat them 9-4.

Meanwhile, Evansville topped VCU 17-11 in Greenville, North Carolina, and is a win away from becoming the third No. 4 regional seed in four years to advance to the super regionals.

Arizona, picked ninth in the Pac-12 in the preseason, swept the conference regular-season and tournament championships and was made host of a regional including four teams with a combined .649 winning percentage.

The Wildcats had gone a combined 10-1 in the two previous regionals they hosted at Hi Corbett Field and made it to the College World Series both times (2012 and 2021).

But they went scoreless over their last 12 innings this weekend, and the loss to No. 2 regional seed Dallas Baptist marked only the second time they’ve been shut out this season.

“It’s glaring to me how good everybody is in college baseball,” Arizona coach Chip Hale said. “You look at Grand Canyon, we played them four times and they beat us three, and they’re supposedly a mid-major. It’s a great thing about college sports in general. We see it in the NCAA basketball tournament. We see big upsets. It’s fun for those teams. It’s not fun for us.”

Arizona managed three hits and four walks in six innings against Patriots starter Jaron DeBerry and just two singles the rest of the way against three relievers. Cam Walty allowed a season-high six runs in four innings, his shortest outing since March 30. He left after Tom Poole hit his second homer of the game with no outs in the fifth.

The Wildcats were 12-for-64 (.188) in the two regional games, including 5-for-27 with runners on base.

Arizona has gone 0-2 in back-to-back tournaments. Last year, the Wildcats went winless in Fayetteville, Arkansas.

Missouri Valley Conference champion Evansville, in the tournament for the first time since 2006, upset No. 16 national seed East Carolina on Friday and won a slugfest against VCU on Saturday. The Purple Aces homered four times, including Brent Widder’s grand slam, and finished with 15 hits. They scored 17 runs for the third time in six games.

The Aces will play East Carolina or VCU in the regional final Sunday and would have to lose twice to not join 2023 Oral Roberts and 2021 South Florida to advance as a No. 4 regional seed.

Seven of the top eight national seeds advanced to regional finals. No. 5 Arkansas lost 7-6 to Kansas State and would have to win an elimination game against Southeast Missouri and beat the Wildcats twice to make the super regionals for the fifth time in six years.

HIGH POINT’S, WELL, HIGH POINT

High Point’s 10-9 walk-off win over Vanderbilt marked the Panthers’ first victory in their program’s first regional appearance and a quick exit for the Commodores.

Vanderbilt went two games and out in the tournament for only the second time in 22 all-time appearances. The Commodores also went 0-2 in 2016.

“That’s kind of new territory for us,” coach Tim Corbin said. “But that falls on myself and you’ve got to look in the mirror and say it’s not good enough, for, at least from the standard that we’ve created.”

The Big South champion Panthers made it to Sunday when Miggy Echazarreta singled into right field to drive in Adam Stuart with one out in the bottom of the ninth.

“Incredible game for our program and for these young men,” coach Joey Hammond said. “We didn’t blink at any point in time. It’s who we are and it’s what we have been doing all year. We are not surprised by it.”

PIRATES PREVAIL

No. 16 national seed East Carolina defended its home field with a 7-6 walk-off win over 2023 College World Series participant Wake Forest. It was an odd elimination game matching probable top-15 picks in next month’s amateur draft, with Wake’s Chase Burns going against Trey Yesavage.

Burns allowed four runs in five innings; Yesavage gave up a run on one hit and four walks in 7⅓. The game, however, came down to the ninth inning and light-hitting Luke Nowak. Wake scored five runs in the top half to go up 6-4, but the Pirates’ first five batters reached in the bottom half before Nowak, batting .191, ended it with a base hit to right.

BIG BATS

No. 1 national seed Tennessee hit four home runs over the first four innings, including Billy Amick’s grand slam, in a 12-6 win over Indiana. … Travis Bazzana homered for the second straight game in Oregon State’s 5-3 win over UC Irvine. … Vance Honeycutt hit his 25th and 26th homers in North Carolina’s 6-2 win over LSU. … Jacob Hinderleider went 5-for-5 against Coastal Carolina, making him the first Clemson player with five hits in a tournament game since 2002. … Garrett Pennington homered twice for North Carolina State in a 6-4 win over South Carolina. … Josh Cameron hit a grand slam as Southeast Missouri State ended a nine-game NCAA tournament losing streak with a 9-3 win over Louisiana Tech.

MOUND MARVELS

Brian Holiday pitched his second straight complete game, and third of the season, in Oklahoma State’s 7-1 win over Florida. He struck out 10 and had a shutout going until Jac Caglianone homered in the ninth. … Evan Aschenbeck did not allow a hit in 4 2/3 innings of relief in No. 3 national seed Texas A&M’s 4-2 win over Texas in 11 innings. … Grayson Grinsell struck out nine batters over seven scoreless innings to help No. 3 seed Oregon beat host UC Santa Barbara 2-1. … Jamie Arnold allowed two runs on three hits and struck out 12 in seven innings of Florida State’s 5-2 win over Stetson. … Kansas State closer Tyson Neighbors threw a season-high 64 pitches over 3 1/3 innings as the Wildcats held off Arkansas 7-6. … Trey Pooser matched his career high with seven innings in Kentucky’s 6-1 win over Illinois, allowing one run on five hits and two walks and striking out seven.

The Associated Press contributed to this report.